November, 9 2023
10:30am – 2:00pm
La Rinconada County Club
14595 Clearview Drive | Los Gatos, CA 95032
Karlene Cimprich, PhD — Stanford School of Medicine
Karlene Cimprich is a Professor at Stanford University with appointments in the Departments of Chemical and Systems Biology and Biochemistry. She received her PhD in chemistry from Harvard University and remained at Harvard for her postdoctoral work with Stuart Schreiber where she cloned and began to study the checkpoint kinase, ATR. Her lab is interested in many aspects of genome instability, a driving force in cancer progression and potential therapeutic vulnerability. She seeks to understand the impact of replication stress signaling and DNA damage tolerance pathways on genome instability as well as the genome instability resulting from interactions between replication and transcription. Her work has also established the central importance of DNA-RNA hybrids or R-loops as a major endogenous source of replication stress and genome instability. Dr. Cimprich serves on several editorial boards, has organized a number of international meetings and is a recipient of numerous awards. Most recently she has been recognized as an AAAS fellow and an American Cancer Society Research Professor.
Joanna Kovalski, PhD — GVL Funded Researcher
University of California, San Francisco
Translation is the process by which the variety and abundance of genetic messages, called mRNAs, are interpreted to synthesize proteins. Typically, dynamic regulation of translation enables a cell to rapidly respond to cues from its environment. However, many cancers have found ways to hijack this adaptive response to promote the expression of the drivers of cancer progression.
The goal of Dr. Kovalski’s research is to understand how cancer signaling remodels protein expression to support tumor development and metastasis. By investigating pancreatic cancer tissues, she will decipher the translational control “code” of the cancer promoting messages that allow the cell to fine-tune key protein levels in pancreatic cancer progression. Ultimately, Dr. Kovalski aims to highlight unique vulnerabilities of cancer cells, resulting in novel therapeutic targets and new clinical treatments for all types of cancer.
Emcee Laura Garcia — NBC Bay Area
Laura Garcia anchors weekday mornings, Today In The Bay and Midday In The Bay alongside Marcus Washington on NBC Bay Area. This multiple Emmy award winning journalist began her career in broadcasting in San Francisco before moving on to report and anchor in Fresno. Prior to joining NBC Bay Area, Laura was an investigative reporter and anchor in Phoenix, Arizona. While there, Laura was honored with The Associated Press Reporter of the Year Award along with multiple Emmy and AP awards for writing and reporting. One of her fondest achievements was accepting an Emmy award in San Francisco for best daytime broadcast. Laura was also recognized with a Best Daytime Newscast Award in the Bay Area by the Bay Area Women in Radio and Television. Laura is an avid participant in various organizations. She is a member of the National Association of Hispanic Journalists and serves on the Board of Trustees of her alma mater, Saint Mary’s College of California in Moraga, where she received her Bachelor of Arts Degree in Communications and Government. Laura also serves on the Board of Directors for the American Cancer Society as well as the Board of the Catholic Professional Business Club. When she’s not on the anchor desk, depending on the season, Laura enjoys golfing, skiing, snowshoeing, reading, cooking and spending time with family and friends. She is the proud mother of triplets Katherine, Claire and Jack.
rag & bone Fashion Show
Raffle by Joe Escobar Diamonds
You are invited to a memorable luncheon!
All proceeds raised benefit the American Cancer Society's
Mission Services and Grand View League Research Funding Initiative.